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Human deficiency diseases have been described for StAR and for all the mitochondrial steroidogenic enzymes, but not for the electron transfer proteins or for the components of the cholesterol import machine. Keywords: 1,25 dihydroxy vitamin D (calcitriol); 1,25(OH)(2)D; 18kDa translocator protein; 3-hydroxy-3-methylglutaryl co-enzyme A; 3β-hydroxysteroid dehydrogenase; 3βHSD; ACAT; ACTH; ANT; CRAC; Cholesterol side chain cleavage; Cholesterol transport; ER; FAD; HDL; HMGCoA; HSL; IMM; IMS; Km; LAL; LDL; LH; MENTAL; MENTHO; MLN64; MLN64 N-terminal; MLN64 N-terminal domain homologue; Michaelis constant; NADPH; NPC; Niemann Pick type C; OMM; Outer mitochondrial membrane; P450scc; PAP7; PBR; PCP; PKA; PKAR1A; PRAX1; PTH; SF1; SOAT; SR-B1; SREBPs; START; StAR; StAR-related lipid transfer domain; Steroidogenesis; Steroidogenic acute regulatory protein; TSPO; TSPO-associated protein 1; TSPO-associated protein 7 (ACBD3); VDAC1; Vitamin D; acyl transferase; adenine nucleotide transporter; adrenocorticotropic hormone; cholesterol recognition amino acid consensus domain; endoplasmic reticulum; flavin adenine dinucleotide; high density lipoproteis; hormone-sensitive neutral lipase; inner mitochondrial membrane; intramembranous space; low-density lipoproteins; luteinizing hormone; lysosomal acid lipase; metastatic lymph node clone 64; mitochondrial cytochrome P450 specific for cholesterol side-chain cleavage; nicotinamide adenine dinucleotide phosphate; outer mitochondrial membrane; parathyroid hormone; peripheral benzodiazepine receptor; phosphate carrier protein; protein kinase A; protein kinase A regulatory subunit 1α; scavenger receptor B1; steroidogenic acute regulatory protein; steroidogenic factor 1; sterol O-acetyltransferase; sterol regulatory element binding proteins; voltage-dependent anion channel, natural bodybuilding competitions 2020. Copyright © 2013 Elsevier Ireland Ltd. How Steroid Hormones Work. Hormones are molecules produced and secreted by endocrine glands in the body.
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